Researchers from the CNRS and Université Nice Sophia Antipolis, France, have demonstrated that methiothepin, a small molecule, can improve the efficiency of chemotherapy by inhibiting the resistance of certain tumours.

Cancerous tumours are also capable of ‘detoxing’, subsequently limiting the efficiency of chemotherapy, and in order to better understand this phenomenon, the research team studied the patched membrane protein, showing that this protein is capable of expelling some of the primary active ingredients of chemotherapy from cancerous cells. The rejection of these toxic substances enables the tumour to eventually survive the treatment.

To read more about this on the Health Europa website go to: Improving the efficiency of chemotherapy with a new molecule